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Lentivirus integration site analysis

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Lentivirus is the most common gene delivery vehicle that is used to establish stable cell lines. After the lentivirus infects the host cell, its RNA genome is first reverse transcribed to DNA and integrated into the host’s genome in a seemingly random fashion. The chosen integration site has significant consequences for both the expression of your transgene and the phenotype of the host cell. Its integration mechanism could affect cellular function if the integration happens within a key gene or near oncogenes. Lentivirus integration site analysis https://qvirus.creative-biogen....e.com/solution/lenti

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