What is Avanafil and how should this medicine be used?

Avanafil is a medication used to treat erectile dysfunction (ED) (i.e., impotence; the inability to get or keep an erection in men). Avanafil belongs to a class of drugs known as phosphodiesterase (PDE) inhibitors.

Avanafil is a medication used to treat erectile dysfunction (ED) (i.e., impotence; the inability to get or keep an erection in men). Avanafil belongs to a class of drugs known as phosphodiesterase (PDE) inhibitors. During sexual stimulation, it increases blood flow to the penis. An erection can result from increased blood flow. Avanafil has no effect on erectile dysfunction or sexual desire. Avanafil has no effect on pregnancy or the spread of sexually transmitted diseases like the human immunodeficiency virus (HIV).


How should this medicine be used?

Avanafil is available as a tablet for oral administration. Avanafil is usually taken with or without food, about 15 minutes before sexual activity by men taking the 100-mg or 200-mg doses. Avanafil is usually taken with or without food, about 30 minutes before sexual activity by men taking the 50-mg dose. Avanafil should not be taken more than once every 24 hours. Follow the instructions on your prescription label exactly, and ask your doctor or pharmacist to explain any parts you don't understand. Avanafil should be taken exactly as prescribed. Do not take more or less of it, or take it more frequently than your doctor has prescribed.

Your doctor will most likely start you on an average dose of avanafil spedra 200 and may adjust it depending on how you respond to the medication. Inform your doctor if avanafil isn't working properly for you or if you experience any side effects.

Request a copy of the manufacturer's information for the patient from your pharmacist or doctor.


What special precautions should I take?

Before taking avanafil,

  • If you are allergic to avanafil spedra 50 mg, any other medications, or any of the ingredients in avanafil tablets, tell your doctor and pharmacist. Consult your pharmacist or patient information for a list of the ingredients.
  • If you are taking or have recently taken riociguat (Adempas) or nitrates such as isosorbide dinitrate (Dilatrate-SR, Isordil, in BiDil), isosorbide mononitrate (Monoket), or nitroglycerin, do not take avanafil (Minitran, Nitro-Dur, Nitromist, Nitrostat, or others). Nitrates are available in the form of tablets, sublingual (under the tongue) tablets, sprays, patches, pastes, and ointments. If you are unsure whether any of your medications contain nitrates, consult your doctor.
  • While taking avanafil, avoid using nitrate-containing street drugs such as amyl nitrate and butyl nitrate ('poppers').
  • Inform your doctor and pharmacist about any other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are currently taking or intend to take. Make sure to include any of the following: alpha blockers Other erectile dysfunction medications or treatments; hypertension medications; nefazodone (Ketek). Your doctor may need to adjust the doses of your medications or closely monitor you for side effects. Many other medications may interact with avanafil, so be sure to inform your doctor about all medications you are taking, including those not on this list.
  • Tell your doctor if you've ever been told by a doctor to avoid sexual activity for medical reasons, if you've had heart surgery in the last 6 months, or if you've ever had an erection that lasted more than 4 hours. Tell your doctor if you have or have ever had angulation, cavernosal fibrosis, or Peyronie's disease; a heart attack; a stroke; an irregular heartbeat; a blocked artery; angina (chest pain); high or low blood pressure; heart failure; or blood cell problems such as sickle cell anaemia (a disease of the red blood cells); ulcers; bleeding problems; or liver or kidney disease. Tell your doctor if you have or have ever had retinitis pigmentosa (a rare inherited eye disease) or if you have ever had severe vision loss, especially if the vision loss was caused by a blockage of blood flow to the nerves that help you see.
  • You should be aware that avanafil 100mg is only intended for male use. Women should avoid taking avanafil, especially if they are pregnant, planning to become pregnant, or are breastfeeding. A pregnant woman who takes avanafil should contact her doctor.
  • Consult your doctor about the safe use of alcoholic beverages while taking avanafil. If you consume a large amount of alcohol (more than three glasses of wine or three shots of whiskey) while taking avanafil, you are more likely to experience dizziness, headache, fast heartbeat, and low blood pressure.
  • Tell your doctor or dentist that you are taking Spedra Avanafil 100 mg if you are having surgery, including dental surgery.
  • Sexual activity can put a strain on your heart, especially if you have heart disease. If you experience chest pain, dizziness, or nausea while sexually active, call your doctor right away and avoid sexual activity until your doctor says otherwise.
  • Inform all of your doctors that you are taking Avanafil 200. If you ever need emergency medical treatment for a heart problem, the doctors will need to know when you last took avanafil.

Avanafil may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away.

  • headache
  • flushing
  • back pain

What should I know about the storage and disposal of this medication?

Keep this medication in its original container, tightly closed, and out of the reach of children. Keep it at room temperature and away from sources of extreme heat and moisture (not in the bathroom).

What other information should I know?

Keep all of your doctor's appointments.

Do not give your medication to anyone else. If you have any questions about refilling your prescription, ask your pharmacist.

It is critical that you keep a written record of all prescription and nonprescription (over-the-counter) medications you are taking, as well as any vitamins, minerals, or other dietary supplements. You should take this list with you whenever you go to the doctor or are admitted to the hospital. It is also important to have this information on hand in case of an emergency.


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